2/1 Genomic equivalence Ch 4

2/6 Genes and Development Ch 4

2/8 Differential gene expression Ch 5

2/13 NO CLASS/MONDAY SCHEDULE

2/15 Differential gene expression Ch 5

2/20 Induction/Signaling Pathways Ch 6

2/22 Induction/Signaling Pathways Ch 6

2/27 Model Systems: Drosophila (Guest Lec: Brennan) Ch 9

3/1 Model Systems: Drosophila (Guest Lec: Brennan) Ch 9

3/6 EXAM #1

3/8 Fertilization Ch 7

3/13 Comparative early development 10,11

3/15 Comparative early development 10,11

3/20 Comparative early development 10,11

3/22 The HOX gene code 11

3/27 Neural Induction, CNS development 10,12

3/29 Nerual Crest 13

4/3 Model Systems: Dictyostelium (Guest Lec: Brazill) 2

4/5 EXAM #2

4/17 Mesoderm development, Somites (Guest Lec: Atit) 14

4/19 Limb Development (Guest lecturer: Atit) 16

4/24 Blood and Vasculature development 15

4/26 Model Systems: Hematopoiesis in Zebrafish

5/1 Selected Organ Development

5/3 Selected Organ Development

5/8 Stem Cell Biology

5/10 Primary Literature

5/15 Primary Literature

LEC DATE REFERENCE LIST (will be updated as necessary)

2/1 (Y) Wakayama and Yanagimachi (1999) Cloning the laboratory mouse. Sem. Cell Dev. Biol. 10:253-258 2/1. 3/13 (Y) Kikyo and Wolffe (2000) Reprogramming nuclei: Insights from Cloning. J. Cell Sci. 113:11-20

2/6 Anderson (2000) Finding the genes that direct mammalian development. Trends Genet. 16:99-102

2/6 (Y) Rajewsky, et. al. (1996) Conditional gene targeting. J. Clin. Invest. 98:600-603

2/15 (Y) Li and Peterson (1999) Locus Control Regions. Trends Genet. 15:403-408

2/20-2/22 (Y) Munroe, et. al. (1999) Hedgehog signal transduction. Exp. Cell. Res. 253:25-33

2/20-2/22 (Y) Polakis, P. (2000) Wnt signaling and cancer. Genes Dev. 14:1837-1851

2/20-2/22 (Y) Piek, et. al. (1999) Specificity, diversity and regulation in TGFb superfamily signaling. FASEB J. 13:2105-24

3/8 (Y) Wassarman, P. (1999) Mammalian Fertilization. Cell 96:175-183 3/13-3/20 (Y) Beddington and Robertson (1999) Axis development and early asymmetry in mammals. Cell 96:195-209

3/22 (N) Deschamps, et. al (1999) Initiation, establishment and maintenance of Hox gene expression patterns in the mouse. Int. J. Dev. Biol. 43:635-650

3/27 (Y) Harland, R. (2000) Neural induction. Curr. Opin. Genet. Dev. 10:357-362

3/29 (N) LaBonne and Bronner-Fraser (1999) Molecular mechanisms of neural crest formation. Ann. Rev. Cell. Dev.Biol. 15:81-112

4/24 (Y) Engel and Murre (1999) Transcription factors in hematopoiesis. Curr. Opin. Genet. Dev. 9:575-579

4/26 (Y) Amatruda and Zon (1999) Dissecting hematopoiesis and disease using the zebrafish. Dev. Biol. 216:1-15

References that are not available as PDF files on the website (marked with "N") will be placed on reserve in the Socrates Center