Hunter College of the City University of New York
Department of Biological Sciences
Graduate Genetics: Fall, 2000                Room: HN C002                             Tuesday and Thursday: 5:20-7:10 PM
course website: http://maxweber.hunter.cuny.edu/eres/                 Staff: Prof. R. Rudner (ROOM 901HN) and TBA
Class Date Day Subject Griffiths other reading Instructor
1 8/31 Th An Introduction to Genetics Henderson
2 9/5 Tu Gene transfer in bacteria and their viruses- Mechanisms of gene transfer in bacteria A. Transformation chap 7 ch 6, Snyder Rudner
3 9/7 Th Gene transfer in bacteria and their viruses- B. Transduction and the genetics of temperate phages ch 7, Snyder Rudner
4 9/12 Tu Gene transfer in bacteria and their viruses- C. Conjugation  ch 5, Snyder Rudner
5 9/14 Th Mutation and adaptation in bacteria 15-16 ch 3, Snyder Rudner
6 9/19 Tu Mutagenic agents, mechanisms of mutagenesis and DNA repair 15-16 ch 3,10, Snyder Rudner
7 9/21 Th The structure and replication of DNA chap 8 ch 1 Snyder Rudner
8 9/26 Tu Genetics of DNA Function chap 9 ch 2 Snyder Rudner
9 9/28 Th Molecular biology of gene function chap 10 ch 1 Snyder Rudner
10 10/3 Tu EXAM
11 10/5 Th Regulation-simple functional units; complex operons chap 11 ch 11 and 13 Snyder Rudner
10/10 Tu Monday's schedule
12 10/12 Th Recombinant DNA technology chap 12 ch 12 Snyder Rudner
13 10/17 Tu Recombination-molecular models chap 19 ch 9 Snyder Rudner
14 10/19 Th Plasmids and transposible elements chap 20 ch 8 Snyder Rudner
15 10/24 Tu Transpositions and nonhomologous recombination chap 20 ch 15 Snyder Rudner
16 10/26 Th Introduction to Genetics; Patterns of inheritance; Mendelian analysis chap. 1,2 TBA
17 10/31 Tu Gene interaction; deviations from Mendelian inheritance chap 4 TBA
18 11/2 Th Linkage I and II; mapping chap 5 TBA
19 11/7 Tu EXAM
20 11/9 Th The eukaryotic chromosome; structure, function and anomalies; chromosome mutations chap 3, 15-18 TBA
21 11/14 Tu lecture 4 cont TBA
22 11/16 Th Introduction to mapping in Neurospora, Drosophila and People chap 6 and handout TBA
23 11/21 Tu Specialized eucaryotic chromosome mapping techniques chap 6 TBA
11/23 Th Thanksgiving
24 11/28 Tu X-inactivation; imprinting handouts TBA
25 11/30 Th More-molecular approaches to gene mapping chap 12-13 TBA
26 12/5 Tu More-molecular approaches to gene mapping, Sherman paradox  chap 12-14 TBA
27 12/7 Th More-molecular approaches to gene mapping
28 12/12 Tu Developmental Genetics chap 23 TBA

All exams must be taken at the times indicated above. Makeup exams will be allowed only under the most extenuating circumstances. Please contact the instructor if there is an emergency; the appropriate instructor must be notified prior to the exam. Excuses for medical reasons require a doctor's note.

Primary Texts: Genetics Analysis, Griffiths et al, 7th edition, Wm. C. Brown. This is a very basic undergraduate text; other up-to-date-texts could be substituted. This book is to be supplemented with additional readings as assigned!
Bacterial and Bacteriophage Genetics, Birge, 3rd edition, 1994, Springer Verlag
Molecular Genetics of Bacteria, Snyder and Champness (1st edition, 1997) ASM Press
Suggested texts for background: Modern Microbial Genetics, Streips and Yasbin (ed.), Wiley-Liss (1990); Molecular Genetics of E. coli, P. Smith-Kearny, Guilford Press, 1989;

back to the top